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BOOK
Janette Sherman:
Life's Delicate Balance Feb. 2005: Special Sale Offer! Despite the fact that the cancer epidemic has not ended, my publisher has decided to take this book out of print. Far too few people understand that cancer is caused by...carcinogens! These are the chemicals, pesticides, endocrine disrupters, and nuclear radiation that are contaminating our environment. We need to educate our friends and colleagues in order to stop this epidemic. The last remaining copies of Life’s Delicate Balance are available for $10.00, plus $4.00 postage. For larger orders, please contact me directly to arrange for shipping.—JDS Life's Delicate Balance defines and documents known causes of breast cancer, and emphasizes the means of prevention. Published at a critical time, this book is applicable to other cancers affecting women, men and children, and useful for all those working toward prevention of cancer. Patients, family members, environmental activists, physicians, and attorneys will find this book informative and insightful.
“A well
informed academic recently expressed disbelief that there were established
causes of cancer beyond diet and exercise! Should said professor read
Life's Delicate Balance by Dr. Janette Sherman, his ignorance would
be quickly dispelled. Considering that 'traditional' risk factors account for no
more than 30% of breast cancers how do we explain the causes of the other 70%?
It is always more convenient to 'blame the cancer victim' while obscuring the
effects of pollution from radiation, carcinogens and unregulated drugs in our
air, food and water.”—Lanie Melamed, Breast
Cancer Action
Montreal.
“Rachel Carson introduced the public to the links between pollution and breast cancer in her groundbreaking Silent Spring (1962) . . . [Life's Delicate Balance] serves as a continued clarion call to clean up the environment.”—Library Journal “It is clear to Sherman—and her arguments are compelling—that while gains may be made by researchers in understanding the mechanisms of disease, true advances in conquering cancer will only come when we 'understand the connections between the loss of personal health and the worldwide pollution from toxic chemicals, ionizing radiation, and endocrine-altering chemicals.' . . . Take action, she counsels, demand real prevention: 'Be outraged by the status quo of waste, sickness, needless early death, loss of human potential, and the loss and degradation of the world's resources.”—Kirkus Reviews “Finally a book about breast cancer that is willing to call things by their real names . . . should be on every cancer activist's shelf.”—Barbara Brenner, Executive Director, Breast Cancer Action “Dr. Sherman probes the synergistic relationship between nuclear fallout and chemical pollutants as the major cause of the breast cancer epidemic in our times ...a fitting successor to (Rachel Carson's) Silent Spring.”—Dr. Jay Gould, Ph.D., Director, Radiation and Public Health Project “Finally, scientific answers telling us what does cause cancer. And it's not all in our genes!”—Rose Marie Williams, President, Cancer Awareness Coalition “[Dr. Sherman] carefully sifts the evidence to make a convincing argument that the causes [of cancer] are chemicals and radiation from the environment.”—Kaye Kilburn, M.D., Professor of Medicine, UCLA School of Medicine and author of Chemical Brain Injury
Copies are $10.00 each plus $3.85
postage for the U. S. or Canada.
(Original publisher’s price was $24.95). For copies, please contact the author
at:
Also very
interesting:
A dangerous gamble: Nuclear power, earthquakes and tsunamis And you will find at www.janettesherman.com also very interesting links ***
Update on Cornell's Breast Cancer and Environmental Risk Factors Program ========= Environmental Health Perspectives Volume 109, Number 5, May 2001 A Rat Mammary Tumor Model Induced by the Organophosphorous Pesticides Parathion and Malathion, Possibly through Acetylcholinesterase Inhibition Gertrudis Cabello,1 Mario Valenzuela,1 Arnaldo Vilaxa,1 Viviana Durán,2 Isolde Rudolph,3 Nicolas Hrepic,4 and Gloria Calaf1,5 1Biology and Health Department, Faculty of Science, University of Tarapacá, Arica, Chile; 2Juan Noé Hospital, Arica, Chile; 3Pharmacology Department, University of Concepción, Concepción, Chile; 4Chemistry Department, Faculty of Science, University of Tarapacá, Arica, Chile; 5Center for Radiological Research, Department of Radiation Oncology, College of Physicians and Surgeons, Columbia University, New York, New York, USA Abstract Environmental chemicals may be involved in the etiology of breast cancers. Many studies have addressed the association between cancer in humans and agricultural pesticide exposure. Organophosphorous pesticides have been used extensively to control mosquito plagues. Parathion and malathion are organophosphorous pesticides extensively used to control a wide range of sucking and chewing pests of field crops, fruits, and vegetables. They have many structural similarities with naturally occurring compounds, and their primary target of action in insects is the nervous system; they inhibit the release of the enzyme acetylcholinesterase at the synaptic junction. Eserine, parathion, and malathion are cholinesterase inhibitors responsible for the hydrolysis of body choline esters, including acetylcholine at cholinergic synapses. Atropine, a parasympatholytic alkaloid, is used as an antidote to acetylcholinesterase inhibitors. The aim of this study was to examine whether pesticides were able to induce malignant transformation of the rat mammary gland and to determine whether alterations induced by these substances increase the cholinergic activation influencing such transformation. These results showed that eserine, parathion, and malathion increased cell proliferation of terminal end buds of the 44-day-old mammary gland of rats, followed by formation of 8.6, 14.3, and 24.3% of mammary carcinomas, respectively, after about 28 months. At the same time, acetylcholinesterase activity decreased in the serum of these animals from 9.78 ± 0.78 U/mL in the control animals to 3.05 ± 0.06 U/mL; 2.57 ± 0.15 U/mL; and 3.88 ± 0.44 U/mL in the eserine-, parathion-, and malathion-treated groups, respectively. However, atropine alone induced a significant (p < 0.05) decrease in the acetylcholinesterase activity from the control value of 9.78 ± 0.78 to 4.38 ± 0.10 for atropine alone, to 1.32 ± 0.06 for atropine in combination with eserine, and 2.39 ± 0.29 for atropine with malathion, and there was no mammary tumor formation. These results indicate that organophosphorous pesticides induce changes in the epithelium of mammary gland influencing the process of carcinogenesis, and such alterations occur at the level of nervous system by increasing the cholinergic stimulation. Key words: acetylcholinesterase, atropine, malathion, parathion, rat mammary cancer. Environ Health Perspect 109:471-479 (2001). [Online 3 May 2001] http://ehpnet1.niehs.nih.gov/docs/2001/109p471-479cabello/abstract.html Address correspondance to G. Cabello, Departamento de Biología y Salud, Facultad de Ciencias, Universidad de Tarapacá, Velásquez 1775, Arica, Chile., E-mail: gcabello@uta.cl We thank S. Rauth for helpful discussions. This work was supported by an Institutional Grant from University of Tarapacá, Arica, Chile, and Avon grant CU51470301. ----------- 11//2000 The Lancet:
Volume 356, Number 9244 25 November 2000 *** The study was large and had a follow-up of 17 years. We have since documented that the fatality rate in women who developed breast cancer rose with increasing serum dieldrin concentrations.4 Dieldrin exposure is, therefore, associated with an increased risk of breast cancer and higher malignancy of the disease. You can read more at
http://www.thelancet.com To be able to read The Lancet one has to subscribe http://www.thelancet.com/ *** 4/99:You find an article about BREAST CANCER , March 4, 1999 under: RACHELS ENVIRONMENT & HEALTH WEEKLY : http://www.rachel.org # 640, Headlines: CHLORINE CHEMISTRY NEWS
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