neurotoxicolgy

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Here you get very interesting information:

Raymond Singer, Ph.D. Neurotoxicology and Neuropsychology: http://www.neurotox.com

Here you also find information about "The Neurotoxicity Screening Survey".

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9/99:

Seventh International Symposium On Neurobehavioral Methods and Effects in Occupational and Environmental Health

Subcortical hypernetabolism and cortical hypometabolism after neurotoxic exposure. Human PET Studies.

Heuser G, Wu J. C.

Brain Imaging Center, University of California, Irvine, CA, USA

Introduction and objectives: Impairment of cortical function after neurotoxic exposure has been documented by SPECT (decreased perfusion) and also by PET (decreased glucose metabolism) in several publications.

Detailed visualization of deap subcortical structures (e.g. olifactory bulb, amygdala, limbiohypothalamic pathways )has only recently become available.

It was our goal to investigate these structures by PET scanning aftere neurotoxic exposure,

Material and Methods: Patients with a documented neurotoxic exposure and with a diagnosis of toxic encephalopathy under went PET studies. Approximately 30 healthy adults served as controls.

Results: we found that a significant numbrt of our patients show not only cortical hypoperfusion (SPECT) and hypometabolism (PET) but - by contrast - hypermetabolism (PET), with potential seizure activity, in deep subcortical structures.

Dicussion and Conclusions: These findings shed light on the possible mechanism of neurotoxic injury and raise the question whether hypermetabolism represents seizure activity in some cases be the result of kindling (by toxic chemicals).

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For those of you who are trying to put together insurance claims or even just learn more about neurological etiology of our assorted illnesses,check this out: http://neurosomatic.cjb.net. The young many who put this together was doing research to help himself understand the complicated terminology in neuroscience. He was pre-med & realized that he had a cross-referenced glossary, so decided to put it on-line for other people.